Normal Developmentof the Respiratory System. A succinct introduction to the prenatal development of the respiratory system describing following stages of the development. Describe each of the stages

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Normal Developmentof the Respiratory System. A succinct introduction to the prenatal development of the respiratory system describing following stages of the development.

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 Describe each of the stages in no more than 8-10sentences.

1.Development of Respiratory Primordium

2.Development of Larynx.

3.Development of Trachea

4Development of Bronchi and Lungs

Respiratory System Development.  List at least10 congenital anomaliesof the respiratory system and describe them in 3-4 sentences

1.Describe in detail molecular mechanisms of the development of cystic fibrosis(10 sentences)and draw a figure showing thepathway defect in CFTR protein.

.The Cardiovascular, Nervous Systemsand Signaling Pathways.

1 Cardiovascular System Developmen.  List 10 congenital heart defects and describe each of them in 3-5sentences.

2. Describeand draw Nkx2.5 transcription factor related signaling pathways in congenital heart defects in no more than 8-10 sentences.

 NervousSystem Development

1.  List 10 congenital abnormalities of the central nervous system and describe them in 5sentences. 

2. Explain TGF-and BMP pathwaysin the neuronaldevelopmentand function(8-10 sentences). Draw the pathwayshowing regulationof signaling molecules

3. Describe and draw the Notch/Delta Pathwayand its role in maintaining Stem Cell Niche

.References:The report should have a minimum of 20 references cited appropriately throughout the text. Use Vancouver style citation

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